Bubble-Up Pizza: Quick Sheet-Pan Pizza Casserole Recipe

If you’re searching for a simple, comforting dinner made with everyday ingredients, bubble-up pizza is worth trying. This casserole-style pizza captures classic pizza flavors in an easy baked dish that’s cheesy, filling, and ideal for busy weeknights. Instead of rolling out dough, you cut refrigerated biscuit dough into pieces and allow it to “bubble up” while baking, resulting in a soft, fluffy texture throughout. It’s also friendly for those watching calories.

This recipe is excellent for feeding a family, making ahead for leftovers, or customizing with whatever pizza toppings you have on hand. If you enjoy pizza but want a hands-off version that’s just as satisfying, bubble-up pizza delivers the comfort and flavor with minimal effort.

The bubble-up format is versatile — if you liked bubble-up enchiladas, you’ll enjoy this pizza variation. It’s become a popular, frequently pinned recipe because it’s easy and adaptable. Thank you to everyone who’s tried and shared these recipes.

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Why You Will Like This Recipe

• Simple, affordable ingredients that most kitchens already have
• No need to roll or stretch pizza dough
• Great way to use leftover meats and toppings
• Cheesy, comforting, and filling
• Perfect for weeknight dinners and casual gatherings
• Highly customizable to suit your favorite pizza flavors
• Reheats well and makes excellent leftovers

Ingredients Needed

• Refrigerated buttermilk biscuits — the base of the dish; when cut into pieces they bake up soft and fluffy to create the “bubble up” texture.
• 96% lean ground beef — provides protein and a classic pizza-meat option. You can swap in pepperoni, cooked sausage, or diced ham.
• Onion powder or 1 small onion, chopped
• Tomato sauce — just enough to coat the dough pieces without making the casserole soggy.
• Garlic, minced — fresh or jarred minced garlic both work well.
• Italian seasoning — a blend of dried herbs like basil and oregano for that familiar pizza flavor.
• Pizza toppings you like — sliced peppers, turkey pepperoni, mushrooms, olives, etc.
• Mozzarella cheese, shredded — part-skim works nicely if you want to reduce calories while keeping a melty texture.
• See the recipe card below for exact measurements and the full ingredient list.

Substitution tips: You can use canned pizza dough cut into pieces instead of biscuits. Use any combination of toppings — bell peppers, onions, mushrooms, or olives all work.

For homemade sauce, consider a basic marinara if you prefer to make your own.

How to Make Bubble Up Pizza

Step 1: Preheat the oven to 350°F (175°C).

Step 2: In a skillet over medium-high heat, brown the ground beef, breaking it up as it cooks. Stir in onion powder (or chopped onion), tomato sauce, basil, minced garlic, and Italian seasoning. Simmer a few minutes to blend flavors.

Step 3: Grease a 9×13-inch baking dish. Quarter the biscuits and scatter the pieces evenly across the bottom of the pan.

Step 4: Spoon the beef and sauce mixture over the biscuit pieces, spreading it evenly. Add your chosen toppings, then top with shredded mozzarella. Bake for about 25 minutes, then check the biscuits with a toothpick; if they are not fully cooked, bake an additional 5–10 minutes until the toothpick comes out clean and the top is golden and bubbly.

Remove from the oven and let the casserole rest for 5 minutes before slicing and serving to allow it to set.

Pro Tips for Bubble Up Pizza

• Cut the biscuit pieces evenly so they bake uniformly.
• Use a light hand with the sauce to avoid a soggy casserole.
• Always check the center for doneness before removing from the oven.
• Add extra cheese in the last few minutes of baking for a golden, bubbly finish.
• Let the dish rest a few minutes after baking so slices hold together better.

Storage

Store leftovers in an airtight container in the refrigerator for up to three days. Reheat in the oven or an air fryer for best texture — these methods preserve the crispness better than microwaving.

Can I make this ahead of time?

Yes — assemble the casserole, cover, and refrigerate until you’re ready to bake. You may need to add a few extra minutes to the baking time when cooking from chilled.

Bubble Up Pizza Variations

• Smoked sausage with caramelized onions
• Pepperoni with fresh tomatoes, mushrooms, and onion
• Pepperoni, sausage, green pepper, onion, and mushroom (meat-lovers)
• BBQ sauce with grilled chicken, pineapple, scallions, and cheddar
• Reuben-style with Thousand Island dressing, sauerkraut, and corned beef or pastrami
• Hawaiian with pineapple and ham
• Meat lovers with pepperoni, sausage, and Canadian bacon
• Other bubble-up casserole ideas include enchilada, meatball sub, or biscuits-and-gravy variations.

Recipe FAQs

If you make this Bubble Up Pizza or try another recipe from the site, please leave a star rating and share your experience in the comments — feedback is always appreciated.

Bubble Up Pizza

• Author: Jenna
• Prep Time: 10 min
• Cook Time: 25 min
• Total Time: 35 min
• Yield: 8 servings
• Category: Easy
• Method: Oven
• Cuisine: American